Getting on TRK
نویسندگان
چکیده
منابع مشابه
On Trk for Retrograde Signaling
Target-derived neurotrophins like nerve growth factor (NGF) mediate biological effects by binding to and activating Trk neurotrophin receptors at nerve terminals. The activated Trk receptors then stimulate local effects at nerve terminals, and retrograde effects at neuronal cell bodies that often reside at considerable distances from the terminals. However, the nature of the retrograde signal h...
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ژورنال
عنوان ژورنال: Nature Reviews Cancer
سال: 2004
ISSN: 1474-175X,1474-1768
DOI: 10.1038/nrc1519